Dr. Alex Cross (Tyler Perry) is a psychologist and police lieutenant who lives in Detroit with his wife, Maria (Carmen Ejogo), their children, Damon and Janelle, and his mother, Nana Mama. He also frequently visits a prisoner, Pop-Pop, who is serving time for a murder. Cross knows her uncle, Daramus Holiday, committed the murder and framed her, but she refuses to tell the truth. When returning home, he learns that Maria is pregnant with their third child, Cross considers accepting a job as an FBI profiler with a 35% pay rise, but fears Maria's reaction, as it would require them to relocate to Washington, D.C. Meanwhile, a man (Matthew Fox) participates in an underground ultimate fighting match, where he flirts with businesswoman Fan Yau (Stephanie Jacobsen). After brutally beating his opponent, the man is invited to Fan Yau's house. There, he sedates, tortures, and kills her. He cuts off all her fingers and steals her laptop.