Humanity has lost much of its developed land due to global warming in the first half of the 21st century. Then, a "Fleet of Fog" loaded with super weapons suddenly appears all over the world. Without the ability to withstand this fleet, humanity was defeated and could no longer travel the seas.
The card game that gathered millions of players all over the world, and has become a part of everyday life. "Cardfight Vanguard". Through this game that has captivated the world, two card fighters, Aichi Sendou and Toshiki Kai, have met many friends and rivals, and grown.
The Genesect Army comes to a mountainous, snowy area that used to be their home. However, three hundred million years have passed, and it is no longer habitable. Suddenly, an avalanche occurs, but Mewtwo arrives and manages to save four of the five Genesect.